In a case-cohort design, what serves as the control group?

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Study for the ACVPM Epidemiology and Biostatistics Exam. Prepare with flashcards and multiple choice questions, with hints and explanations for each. Be exam-ready!

Multiple Choice

In a case-cohort design, what serves as the control group?

Explanation:
In a case-cohort design, the comparison group is formed from a subcohort that is a random sample of the full cohort chosen at baseline. This subcohort represents the exposure distribution of the source population and serves as the control group for analysis. All incident cases in the entire cohort are identified, and exposure data are collected for both the subcohort and these cases. The efficiency comes from measuring exposures in just the subcohort plus the cases, rather than in the entire cohort. So the best description of the control group is a random sample of the full cohort.

In a case-cohort design, the comparison group is formed from a subcohort that is a random sample of the full cohort chosen at baseline. This subcohort represents the exposure distribution of the source population and serves as the control group for analysis. All incident cases in the entire cohort are identified, and exposure data are collected for both the subcohort and these cases. The efficiency comes from measuring exposures in just the subcohort plus the cases, rather than in the entire cohort. So the best description of the control group is a random sample of the full cohort.

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